Cervical cancer prevention among older women – challenges in screening, diagnostic workup and treatment

Cervical cancer incidence and mortality have declined dramatically after screening for cervical was implemented. Yet, studies reported high rates at older age despite low HPV prevalence of precursor lesions. The underlying reason these findings remains unclear. However, it is well known that the impact depends not only on uptake effectiveness but also diagnostic workup (ie colposcopy), treatment follow-up. In women, sensitivity performance colposcopy are impaired due to age-dependent changes cervix. this commentary, we aimed discuss challenges in clinical management identify crucial areas particular interest future research.